MK 0354
| SMILES | n1[nH]nc(n1)c1n[nH]c2c1CCC2 |
| InChIKey | LTQYSJKGRPGMPO-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 4 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 1 |
| Molecular weight (Da) | 176.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| HCA2 | HCAR2 | Human | Hydroxycarboxylic acid | A | pKi | 6.3 | 6.3 | 6.3 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| HCA2 | HCAR2 | Mouse | Hydroxycarboxylic acid | A | pEC50 | 5.97 | 6.19 | 6.4 | ChEMBL |
| HCA2 | HCAR2 | Mouse | Hydroxycarboxylic acid | A | pIC50 | 5.92 | 5.92 | 5.92 | ChEMBL |
| HCA2 | HCAR2 | Human | Hydroxycarboxylic acid | A | pIC50 | 5.82 | 5.82 | 5.82 | ChEMBL |
| HCA2 | HCAR2 | Human | Hydroxycarboxylic acid | A | pEC50 | 5.64 | 6.12 | 6.54 | ChEMBL |
| HCA2 | HCAR2 | Human | Hydroxycarboxylic acid | A | pEC50 | 5.78 | 5.78 | 5.78 | Guide to Pharmacology |
| HCA2 | HCAR2 | Rat | Hydroxycarboxylic acid | A | pEC50 | 5.64 | 5.64 | 5.64 | ChEMBL |