IMIQUIMOD


SMILES CC(C)Cn1cnc2c(N)nc3ccccc3c21
InChIKey DOUYETYNHWVLEO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 240.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Human Adrenoceptors A pKi 5.89 5.89 5.89 ChEMBL
H2 HRH2 Human Histamine A pKi 5.83 5.83 5.83 ChEMBL
A2A AA2AR Human Adenosine A pKi 5.53 5.53 5.53 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.23 8.23 8.23 Drug Central
H2 HRH2 Human Histamine A pKi 8.23 8.23 8.23 Drug Central
A2A AA2AR Human Adenosine A pKi 8.26 8.26 8.26 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Human Adrenoceptors A pIC50 5.58 5.58 5.58 ChEMBL
H2 HRH2 Human Histamine A pIC50 5.82 5.82 5.82 ChEMBL
A2A AA2AR Human Adenosine A pIC50 5.27 5.27 5.27 ChEMBL