neuropeptide FF


SMILES None
InChIKey None
Sequence FLFQPQRF

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Endogenous
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPFF1 NPFF1 Human Neuropeptide FF/neuropeptide AF A pKi 8.5 9.2 9.9 Guide to Pharmacology
NPFF2 NPFF2 Human Neuropeptide FF/neuropeptide AF A pKi 9.7 9.7 9.7 Guide to Pharmacology
NPFF2 NPFF2 Mouse Neuropeptide FF/neuropeptide AF A pKi 8.96 8.96 8.96 ChEMBL
NPFF2 NPFF2 Rat Neuropeptide FF/neuropeptide AF A pKi 9.68 9.68 9.68 ChEMBL
NPFF1 NPFF1 Human Neuropeptide FF/neuropeptide AF A pKi 10.22 10.22 10.22 ChEMBL
NPFF1 NPFF1 Human Neuropeptide FF/neuropeptide AF A pKd 8.95 8.95 8.95 ChEMBL
NPFF2 NPFF2 Human Neuropeptide FF/neuropeptide AF A pKi 8.92 9.81 10.7 ChEMBL
NPFF2 NPFF2 Human Neuropeptide FF/neuropeptide AF A pKd 9.43 9.55 9.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MAS1 MAS Mouse A orphans A pEC50 6.4 6.4 6.4 Guide to Pharmacology
NPFF1 NPFF1 Human Neuropeptide FF/neuropeptide AF A pEC50 6.56 6.64 6.8 ChEMBL
NPFF2 NPFF2 Human Neuropeptide FF/neuropeptide AF A pEC50 6.21 7.4 8.57 ChEMBL