ONO-AE1-259


SMILES C=CCC1(CCC1)[C@H](C/C=C/[C@H]1[C@H](O)C[C@H]([C@@H]1C/C=C\CCCC(=O)O)Cl)O
InChIKey XXTBGKDWFYXGDZ-KJCKJCAZSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 12
Molecular weight (Da) 410.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Mouse Prostanoid A pKi 8.5 8.5 8.5 Guide to Pharmacology
IP PI2R Human Prostanoid A pKi 5.0 5.0 5.0 ChEMBL
EP1 PE2R1 Human Prostanoid A pKi 5.89 5.89 5.89 ChEMBL
EP2 PE2R2 Human Prostanoid A pKi 8.77 8.77 8.77 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 5.57 5.57 5.57 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 5.64 5.64 5.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 8.74 8.74 8.74 ChEMBL