CHEMBL1323386


SMILES O=S1(=O)c2ccccc2N(Cc2ccc(Cl)cc2F)c2ccccc21
InChIKey JTSLXNXALUZZHT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 373.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.28 5.28 5.28 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 4.88 4.88 4.88 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.41 5.41 5.41 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.56 5.56 5.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database