orforglipron



orforglipron

No image available
SMILES Cc1cc(-n2nc3c(c2-n2ccn(-c4ccc5c(cnn5C)c4F)c2=O)[C@H](C)N(C(=O)c2cc4cc([C@H]5CCOC(C)(C)C5)ccc4n2[C@@]2(c4noc(=O)[nH]4)C[C@@H]2C)CC3)cc(C)c1F
InChIKey USUWIEBBBWHKNI-KHIFEHGGSA-N

Chemical Properties

Hydrogen bond acceptors 13
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 882.4

Database connections

Structure pdb 6XOX 7E14

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

orforglipron

No image available

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 0
Phase III 2
Phase IV 0

Database connections

Structure pdb 6XOX 7E14

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score