PCO371


SMILES O=C1NC(=NC12CCN(S(=O)(CCC3=C(C=C(N4C(NC(C4(C)C)=O)=O)C=C3C)C)=O)CC2)C5=CC=C(C=C5)OC(F)(F)F
InChIKey LDZJFVOUPUFOHX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 635.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 8GW8 8JR9

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PTH1 PTH1R Human Parathyroid hormone B1 pEC50 5.39 5.39 5.39 Guide to Pharmacology
PTH1 PTH1R Human Parathyroid hormone B1 pEC50 5.39 5.39 5.39 ChEMBL
PTH1 PTH1R Rat Parathyroid hormone B1 pEC50 5.62 5.62 5.62 ChEMBL