peptide YY
| SMILES | None |
| InChIKey | IXMRLEGHWROJAA-HDTKZREISA-N |
| Sequence | YPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Endogenous/Surrogate | Endogenous |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| Y2 | NPY2R | Human | Neuropeptide Y | A | pKi | 9.5 | 9.5 | 9.5 | Guide to Pharmacology |
| Y5 | NPY5R | Human | Neuropeptide Y | A | pKi | 8.9 | 8.9 | 8.9 | Guide to Pharmacology |
| Y1 | NPY1R | Rat | Neuropeptide Y | A | pKi | 10.2 | 10.2 | 10.2 | Guide to Pharmacology |
| Y4 | NPY4R | Rat | Neuropeptide Y | A | pKi | 6.3 | 6.85 | 8.5 | Guide to Pharmacology |
| Y5 | NPY5R | Rat | Neuropeptide Y | A | pKi | 9.0 | 9.0 | 9.0 | Guide to Pharmacology |
| Y2 | Q9ERC0 | Rat | Neuropeptide Y | A | pKi | 10.0 | 10.0 | 10.0 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| Y4 | NPY4R | Mouse | Neuropeptide Y | A | pIC50 | 6.3 | 7.4 | 8.5 | Guide to Pharmacology |
| Y2 | Q9ERC0 | Rat | Neuropeptide Y | A | pIC50 | 9.85 | 9.85 | 9.85 | ChEMBL |
| Y2 | NPY2R | Human | Neuropeptide Y | A | pIC50 | 10.15 | 10.15 | 10.15 | ChEMBL |
| Y1 | NPY1R | Human | Neuropeptide Y | A | pIC50 | 10.7 | 10.7 | 10.7 | ChEMBL |