SHU9119


SMILES None
InChIKey GGYWLZFXFKFWKL-XOJVSUSESA-N
Sequence CDHARWCK

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 6W25

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKd 9.2 9.2 9.2 Guide to Pharmacology
MC3 MC3R Human Melanocortin A pKi 8.9 9.0 9.1 Guide to Pharmacology
MC4 MC4R Human Melanocortin A pKi 9.4 9.5 9.6 Guide to Pharmacology
MC5 MC5R Human Melanocortin A pKd 9.0 9.0 9.0 Guide to Pharmacology
MC3 MC3R Rat Melanocortin A pKi 9.1 9.1 9.1 Guide to Pharmacology
MC3 MC3R Mouse Melanocortin A pKd 8.7 9.1 9.5 ChEMBL
MC4 MC4R Mouse Melanocortin A pKd 9.7 10.05 10.4 ChEMBL
MC3 MC3R Human Melanocortin A pKi 9.89 9.89 9.89 ChEMBL
MC4 MC4R Human Melanocortin A pKi 10.54 10.54 10.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 8.62 8.63 8.64 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 9.17 9.18 9.19 ChEMBL
MC3 MC3R Mouse Melanocortin A pEC50 8.52 8.52 8.52 ChEMBL
MC3 MC3R Human Melanocortin A pIC50 7.08 7.08 7.08 ChEMBL
MC4 MC4R Human Melanocortin A pIC50 7.42 7.42 7.42 ChEMBL