ArrestinDb

SNC80

Agent/drug
Bioactivity

SNC80

SMILES	C=CCN1C[C@H](C)N([C@H](c2ccc(C(=O)N(CC)CC)cc2)c2cccc(OC)c2)C[C@H]1C
InChIKey	KQWVAUSXZDRQPZ-UMTXDNHDSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	9
Molecular weight (Da)	449.3

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	7.20	7.20	7.20	Guide to Pharmacology
δ	OPRD	Mouse	Opioid	A	pKi	7.78	8.71	9.15	ChEMBL
δ	OPRD	Rat	Opioid	A	pKi	8.25	8.69	8.92	ChEMBL
δ	OPRD	Human	Opioid	A	pKi	8.77	8.87	8.92	ChEMBL
δ	OPRD	Human	Opioid	A	pKd	6.20	6.20	6.20	ChEMBL
κ	OPRK	Mouse	Opioid	A	pKi	5.56	5.71	5.87	ChEMBL
κ	OPRK	Guinea pig	Opioid	A	pKi	4.93	5.15	5.45	ChEMBL
κ	OPRK	Guinea pig	Opioid	A	pKd	6.20	6.20	6.20	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	5.38	5.43	5.45	ChEMBL
κ	OPRK	Rat	Opioid	A	pKi	5.45	5.45	5.45	ChEMBL
μ	OPRM	Mouse	Opioid	A	pKi	5.62	5.89	6.16	ChEMBL
μ	OPRM	Rat	Opioid	A	pKi	5.09	5.68	5.89	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	5.89	6.17	6.45	ChEMBL

Showing 1 to 13 of 13 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Mouse	Opioid	A	pIC50	6.19	7.99	9.10	ChEMBL
δ	OPRD	Rat	Opioid	A	pIC50	6.37	8.19	8.97	ChEMBL
δ	OPRD	Rat	Opioid	A	pEC50	6.78	6.78	6.78	ChEMBL
δ	OPRD	Human	Opioid	A	pEC50	6.12	8.03	8.77	ChEMBL
δ	OPRD	Human	Opioid	A	pIC50	7.31	8.55	8.89	ChEMBL
κ	OPRK	Guinea pig	Opioid	A	pIC50	5.15	5.46	5.90	ChEMBL
κ	OPRK	Human	Opioid	A	pIC50	5.61	5.61	5.61	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	5.28	5.28	5.28	ChEMBL
κ	OPRK	Rat	Opioid	A	pIC50	5.44	5.44	5.44	ChEMBL
μ	OPRM	Mouse	Opioid	A	pIC50	5.22	5.22	5.22	ChEMBL
μ	OPRM	Rat	Opioid	A	pIC50	5.03	5.37	5.61	ChEMBL
μ	OPRM	Human	Opioid	A	pIC50	5.32	6.11	6.50	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	9.85	9.85	9.85	ChEMBL

Showing 1 to 13 of 13 entries

SNC80

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.