(S)-UH 301


SMILES CCCN([C@H]1CCc2c(C1)c(O)ccc2F)CCC
InChIKey FNKBVTBXFLSTPB-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 265.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.9 7.9 7.9 Guide to Pharmacology
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 5.5 5.5 5.5 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.21 6.27 6.4 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.4 7.21 7.61 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKd 7.6 7.6 7.6 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.06 7.06 7.06 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.42 5.42 5.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.75 4.96 5.2 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.4 4.4 4.4 ChEMBL