tifluadom


SMILES O=C(c1ccsc1)NCC1CN=C(c2c(N1C)cccc2)c1ccccc1F
InChIKey NPGABYHTDVGGJK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 393.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK1 CCKAR Rat Cholecystokinin A pKi 7.33 7.33 7.33 ChEMBL
κ OPRK Guinea pig Opioid A pKi 9.11 9.11 9.11 ChEMBL
δ OPRD Human Opioid A pKi 6.82 6.82 6.82 ChEMBL
κ OPRK Human Opioid A pKi 9.77 9.77 9.77 ChEMBL
κ OPRK Human Opioid A pKi 8.8 8.8 8.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK1 CCKAR Rat Cholecystokinin A pIC50 7.33 7.33 7.33 ChEMBL