CHEMBL140099


SMILES N#Cc1ccc2[nH]c(CN3CCN(c4ccccc4)CC3)cc2c1
InChIKey TWVIJESEEXGVPP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 316.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 4.89 4.89 4.89 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 4.89 4.89 4.89 ChEMBL
D4 DRD4 Human Dopamine A pKi 9.28 9.28 9.28 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.77 5.77 5.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.51 5.92 6.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database