CHEMBL14208


SMILES CC(C)Oc1ccccc1OC(C)C1=NCCN1
InChIKey YQBKUZKHVPTFOO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 248.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.8 5.8 5.8 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.4 6.4 6.4 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.08 7.08 7.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 5.76 5.76 5.76 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 7.0 7.0 7.0 ChEMBL