CHEMBL145793


SMILES COc1cc2nc3c(c(O)c2cc1OC)CCC(CNC(=O)c1ccco1)C3
InChIKey OOWAZNPOGJVTHK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 382.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.53 6.53 6.53 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 5.94 5.94 5.94 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 5.59 5.59 5.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database