CHEMBL152391


SMILES COc1cccc(C(=O)NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c1
InChIKey LNAUHJFPPUQFSP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 435.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.05 8.05 8.05 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.85 5.85 5.85 ChEMBL
D3 DRD3 Rat Dopamine A pKi 9.57 9.57 9.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database