CHEMBL103479


SMILES CN1CCC(c2c[nH]c3ccc(NC(=O)c4ccc(F)cc4)nc23)CC1
InChIKey RUJUSCZEDDAGAW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 352.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.12 8.12 8.12 ChEMBL
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 6.18 6.18 6.18 ChEMBL
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 5.4 5.4 5.4 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.14 6.14 6.14 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.72 5.72 5.72 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.32 5.32 5.32 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.25 7.25 7.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database