CHEMBL1576791


SMILES O=S(=O)(Nc1cc(Sc2cccc3cccnc23)c(O)c2ccccc12)c1ccccc1
InChIKey PQIKPRFFZWZBIW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 458.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.59 4.59 4.59 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 4.81 4.81 4.81 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.47 4.47 4.47 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.62 4.62 4.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database