CHEMBL1580288


SMILES CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCc3ccccc3C2)s1
InChIKey XWBNXNPYMCYTKF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 482.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.8 4.8 4.8 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.82 6.89 6.92 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.5 6.52 6.53 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.91 4.91 4.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database