ArrestinDb

CHEMBL167753

Agent/drug
Bioactivity

CHEMBL167753

SMILES	Cn1cc2c(nc(NC(=O)Nc3ccc(Cl)cc3)n3nc(-c4ccco4)nc23)n1
InChIKey	YNNNCAAPQRZSHQ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	8
Hydrogen bond donors	2
Rotatable bonds	3
Molecular weight (Da)	408.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

A₁	AA1R	Human	Adenosine	A	pKi	6.37	6.37	6.37	ChEMBL
A_2A	AA2AR	Human	Adenosine	A	pKi	6.74	6.75	6.75	ChEMBL
A_2B	AA2BR	Human	Adenosine	A	pKi	6.89	6.89	6.89	ChEMBL
A₃	AA3R	Human	Adenosine	A	pKi	6.54	9.04	9.54	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

A₃	AA3R	Human	Adenosine	A	pIC50	8.62	8.62	8.62	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL167753

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.