CHEMBL160952


SMILES C#Cc1cccc2c(CN3CCN(c4ccc(Cl)cc4)CC3)cnn12
InChIKey NVYMBZSBOQRSFH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 350.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 6.09 6.09 6.09 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.91 8.91 8.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.34 5.34 5.34 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.21 5.36 5.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database