CHEMBL1631535


SMILES Cc1ccc2c(N3CCN(CCc4cccc(NS(C)(=O)=O)c4)CC3)cccc2n1
InChIKey XKHJTHWUWGJDOX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 9.1 9.1 9.1 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 9.9 9.9 9.9 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.5 5.5 5.5 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.1 6.1 6.1 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.1 9.1 9.1 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.4 6.4 6.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database