CHEMBL1642123


SMILES CC1CC(=O)c2c(N3CCN(C)CC3)cccc2N1S(=O)(=O)c1ccc2ccccc2c1
InChIKey JYJNPJVGVPZHKA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 449.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.7 5.7 5.7 ChEMBL
D4 DRD4 Human Dopamine A pIC50 5.26 5.26 5.26 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 8.1 8.1 8.1 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 7.52 7.52 7.52 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.32 6.32 6.32 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 7.32 7.32 7.32 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 5.92 5.92 5.92 ChEMBL