(R)-METOPROLOL


SMILES COCCc1ccc(OC[C@H](O)CNC(C)C)cc1
InChIKey IUBSYMUCCVWXPE-CQSZACIVSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 267.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 B0FL73 Guinea pig Adrenoceptors A pKd 6.13 6.13 6.13 ChEMBL
β2 ADRB2 Guinea pig Adrenoceptors A pKd 5.24 5.24 5.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.5 4.5 4.5 ChEMBL