CHEMBL1767159


SMILES O=c1c2ccccc2c(Cc2ccc(Cl)cc2)nn1C1CCCN(Cc2ccc(OCCCN3CCCCCC3)cc2)CC1
InChIKey QYAXGGUCDQSHIT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 612.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.9 6.9 6.9 ChEMBL
H1 HRH1 Human Histamine A pKi 7.3 7.3 7.3 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.0 7.0 7.0 ChEMBL
H3 HRH3 Human Histamine A pKi 9.3 9.3 9.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database