CHEMBL177064


SMILES COc1ccccc1N1CCN(Cc2ccn(-c3ccccc3C)c2)CC1
InChIKey DTNYAHQRGGTLBQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 361.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.68 7.68 7.68 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.68 8.18 8.37 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.39 7.39 7.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database