CHEMBL1928132


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(COCCOCCOCCOCCOCCOCCOCCOCCOCc3ccc(C(=O)NCCCCN4CCN(c5ccccc5OC)CC4)cc3)cc2)CC1
InChIKey AMKQYZPSQCPQGB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 17
Hydrogen bond donors 2
Rotatable bonds 44
Molecular weight (Da) 1128.7

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A Q9TSW7 Pig Adrenoceptors A pKi 8.46 8.46 8.46 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.85 6.85 6.85 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.52 9.52 9.52 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.42 7.61 7.8 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.92 5.92 5.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database