CHEMBL178673


SMILES COc1cc2nc(N3CCN(C(=O)CC4CCSS4)CC3)nc(N)c2cc1OC
InChIKey WLZJELZXDHZVLY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 435.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKd 9.04 9.04 9.04 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 8.99 8.99 8.99 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 9.51 9.51 9.51 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 9.0 9.0 9.0 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.41 9.41 9.41 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 9.54 9.54 9.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database