CHEMBL1940408


SMILES Fc1ccc(CCCCN2CCN(c3ccc(Cl)cc3)CC2)cc1
InChIKey ARWONURFSGKTJW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 346.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.11 8.11 8.11 ChEMBL
D5 DRD5 Human Dopamine A pKi 5.75 5.75 5.75 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.23 6.23 6.23 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.58 6.58 6.58 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.09 7.09 7.09 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.95 6.95 6.95 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.55 6.55 6.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database