CHEMBL1940409


SMILES Fc1ccc(SCCCN2CCN(c3ccc(Cl)cc3)CC2)cc1
InChIKey QEVFANOTWOZMFN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 364.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.06 8.06 8.06 ChEMBL
D5 DRD5 Human Dopamine A pKi 5.55 5.55 5.55 ChEMBL
D1 DRD1 Human Dopamine A pKi 7.28 7.28 7.28 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.38 6.38 6.38 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.68 6.68 6.68 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database