CHEMBL180086


SMILES CC(Nc1nc(N)nc(NCCc2cccs2)n1)c1ccc(F)cc1
InChIKey CWQTXKTYLNBFFC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 358.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database