CHEMBL1813276


SMILES Cc1c(CC(=O)O)c2cc(F)ccc2n1C(=O)c1ccc(OC[C@@H]2CN(C)c3ccccc3O2)cc1Cl
InChIKey ZTQFWIHDGMZBBP-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 522.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FP PF2R Mouse Prostanoid A pKi 5.92 5.92 5.92 ChEMBL
DP1 PD2R Mouse Prostanoid A pKi 8.28 8.28 8.28 ChEMBL
EP2 PE2R2 Mouse Prostanoid A pKi 6.43 6.43 6.43 ChEMBL
EP4 PE2R4 Mouse Prostanoid A pKi 5.39 5.39 5.39 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 5.5 5.5 5.5 ChEMBL
IP PI2R Human Prostanoid A pKi 6.7 6.7 6.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Mouse Prostanoid A pIC50 8.8 8.8 8.8 ChEMBL