CHEMBL181874


SMILES COc1ccccc1N1CCN(Cc2ccn(-c3ccccc3C#N)c2)CC1
InChIKey ZWXPEPNHGUBVMQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 372.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.27 8.27 8.27 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.47 7.47 7.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database