CHEMBL197664


SMILES CN(C)CCc1cn(C)c2cccc(O)c12
InChIKey MZZRFEIDRWKTKJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 218.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 7.32 7.32 7.32 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.42 7.42 7.42 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.48 7.82 8.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.05 6.05 6.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 7.5 7.5 7.5 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 8.02 8.02 8.02 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.92 7.92 7.92 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.2 6.2 6.2 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 7.06 7.06 7.06 ChEMBL