AS-19


SMILES CN([C@H]1CCc2c(C1)cccc2c1c(C)nn(c1C)C)C
InChIKey BTTOYOKCLDAHHO-HNNXBMFYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 283.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 9.22 9.22 9.22 Guide to Pharmacology
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 7.01 7.01 7.01 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.92 8.96 9.22 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.62 6.91 7.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database