(2R,3R)-APDC


SMILES OC(=O)[C@@H]1NC[C@@](C1)(N)C(=O)O
InChIKey XZFMJVJDSYRWDQ-AWFVSMACSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 2
Molecular weight (Da) 174.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 5.0 5.0 5.0 Guide to Pharmacology
mGlu3 GRM3 Human Metabotropic glutamate C pKi 5.3 5.3 5.3 Guide to Pharmacology
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.35 6.35 6.35 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.39 6.39 6.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pEC50 4.0 4.0 4.0 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 6.32 6.51 6.7 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 5.52 5.52 5.52 ChEMBL
mGlu3 GRM3 Rat Metabotropic glutamate C pEC50 5.77 5.77 5.77 ChEMBL