CHEMBL185369


SMILES CCCCOc1ccc(C(=O)n2c(C)c(CCCC(=O)O)c3cc(OC)ccc32)cc1
InChIKey OGNGNXGCXSFDBN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 423.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Mouse Prostanoid A pKi 6.72 6.72 6.72 ChEMBL
EP2 PE2R2 Mouse Prostanoid A pKi 5.57 5.57 5.57 ChEMBL
EP4 PE2R4 Mouse Prostanoid A pKi 5.82 5.82 5.82 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 5.62 5.62 5.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Mouse Prostanoid A pIC50 6.04 6.04 6.04 ChEMBL