benperidol


SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)n1c(=O)[nH]c2c1cccc2
InChIKey FEBOTPHFXYHVPL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 381.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 10.57 10.57 10.57 Guide to Pharmacology
D4 DRD4 Human Dopamine A pKi 10.18 10.18 10.18 Guide to Pharmacology
D3 DRD3 Human Dopamine A pKi 9.54 9.54 9.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 10.57 10.57 10.57 ChEMBL
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 8.42 8.59 8.92 PDSP Ki database
D2 DRD2 Bovine Dopamine A pKi 9.48 9.48 9.48 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 10.57 10.57 10.57 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 10.18 10.18 10.18 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.05 8.05 8.05 Drug Central
D2 DRD2 Human Dopamine A pKi 7.98 7.98 7.98 Drug Central
D3 DRD3 Human Dopamine A pKi 7.99 7.99 7.99 Drug Central
D4 DRD4 Human Dopamine A pKi 8.06 8.06 8.06 Drug Central
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.92 8.92 8.92 ChEMBL
D4 DRD4 Human Dopamine A pKi 10.18 10.18 10.18 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 5.39 5.39 5.39 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database