CHEMBL108804


SMILES CS(=O)(=O)Nc1c(O)ccc2c1CCCC2c1c[nH]cn1
InChIKey RMRXQQJMELOBDK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 307.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Rat Adrenoceptors A pKi 7.32 7.32 7.32 ChEMBL
α1B ADA1B Golden hamster Adrenoceptors A pKi 5.6 5.6 5.6 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 7.44 7.44 7.44 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.35 7.35 7.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Rabbit Adrenoceptors A pEC50 7.77 7.77 7.77 ChEMBL
α1B ADA1B Rat Adrenoceptors A pEC50 6.64 6.64 6.64 ChEMBL