CHEMBL193435


SMILES CN(C)C[C@H]1CC2c3ccccc3Oc3ccc(Br)cc3[C@H]2O1
InChIKey FXHLGRYCQSRFHY-MQSINFNDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 373.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pKi 6.13 6.13 6.13 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.46 7.46 7.46 ChEMBL
H1 HRH1 Human Histamine A pKi 7.38 7.38 7.38 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.39 6.39 6.39 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.81 6.81 6.81 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.05 8.05 8.05 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.82 7.82 7.82 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.18 7.18 7.18 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.02 7.02 7.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database