cicloprolol


SMILES OC(COc1ccc(cc1)OCCOCC1CC1)CNC(C)C
InChIKey JNDJPKHYZWRRIS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 12
Molecular weight (Da) 323.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pKi 8.0 8.0 8.0 Guide to Pharmacology
β2 ADRB2 Human Adrenoceptors A pKi 6.2 6.2 6.2 Guide to Pharmacology
β1 ADRB1 Human Adrenoceptors A pKi 8.1 8.1 8.1 Drug Central
β2 ADRB2 Human Adrenoceptors A pKi 8.21 8.21 8.21 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database