CHEMBL1946257


SMILES O=C(CCCCN1CCCN(c2ccc(Cl)cc2)CC1)c1nc2ccccc2s1
InChIKey QLTASWSCCMMISJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 427.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 5.92 5.92 5.92 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.55 5.55 5.55 ChEMBL
H1 HRH1 Human Histamine A pKi 6.89 6.89 6.89 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.23 5.23 5.23 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.98 5.98 5.98 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.7 5.7 5.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database