CHEMBL1962961


SMILES O=S(=O)(c1cnc2ccccc2c1)N1CCC(CCN2CCN(c3ccc(Cl)cc3)CC2)CC1
InChIKey OGFFWRBVNOYKPL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 498.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.4 7.4 7.4 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.25 7.25 7.25 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.08 5.08 5.08 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 4.61 4.61 4.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database