ArrestinDb

ITOPRIDE

Agent/drug
Bioactivity

ITOPRIDE

SMILES	COc1ccc(C(=O)NCc2ccc(OCCN(C)C)cc2)cc1OC
InChIKey	QQQIECGTIMUVDS-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	9
Molecular weight (Da)	358.2

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

No bioactivity data available.

ITOPRIDE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 2

Phase III 1

Approved Yes

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	Class A	Constipation	ME05.0		0.074	2	Yes
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	Class A	Dyspepsia	MD92		0.560	4	Yes
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	Class A	Gastro-oesophageal reflux disease, unspecified	DA22.Z		0.558	4	Yes
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	Class A	Gastroparesis	DA41.00		0.555	4	Yes
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	Class A	Irritable bowel syndrome, type unspecified	DD91.0Z		0.074	2	Yes
DRD2	D₂ receptor	Dopamine receptors	Aminergic receptors	Class A	Peritonitis, unspecified	DC50.Z		0.259	3	Yes

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