CHEMBL1963103


SMILES O=S(=O)(c1cncc2ccccc12)N1CCC(CCN2CCN(c3ccc(Cl)cc3)CC2)CC1
InChIKey PTCABQYHORAOLY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 498.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.33 7.33 7.33 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.22 7.22 7.22 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.49 5.49 5.49 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 4.78 4.78 4.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database