DAROTROPIUM


SMILES C[N+]1(C)[C@H]2CC[C@@H]1C[C@H](CC(C#N)(c1ccccc1)c1ccccc1)C2
InChIKey BKLAJZNVMHLXAP-QYEXWFEISA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 345.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 10.2 10.21 10.22 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKd 10.0 10.47 10.7 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKd 10.3 10.3 10.3 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.77 9.79 9.8 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 10.3 10.3 10.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database