CHEMBL211135


SMILES Clc1ccc(N2CCN(Cc3cn4nc(Cl)ccc4n3)CC2)cc1
InChIKey AGMWTWZTMQSDHF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 361.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.04 6.04 6.04 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.26 5.26 5.26 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.7 8.7 8.7 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.11 5.11 5.11 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.41 6.41 6.41 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.92 5.0 5.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database