CHEMBL2113264


SMILES CC(C)[C@H]1CNC[C@H]2c3cccc(C(F)(F)F)c3C(=O)N12
InChIKey KXGOSZXOKPHJFK-NEPJUHHUSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 298.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.42 7.42 7.42 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.15 8.15 8.15 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 7.25 7.25 7.25 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.85 7.85 7.85 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.0 8.0 8.0 ChEMBL