CHEMBL198993


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(F)nc2)CC1
InChIKey DOVTZHSQYCZIIX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.2 5.2 5.2 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.89 6.89 6.89 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.85 7.85 7.85 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.62 6.71 6.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database