Cp-1


SMILES CNC(=O)[C@H](N1CCc2c([C@@H]1CCc1ccc(nc1)C(F)(F)F)cc(c(c2)OC)OC)c1ccccc1
InChIKey FIINKDGVMNTVCW-BKMJKUGQSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 513.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 7.59 7.59 7.59 Guide to Pharmacology
OX2 OX2R Human Orexin A pKi 9.15 9.15 9.15 Guide to Pharmacology
OX2 OX2R Human Orexin A pKd 9.2 9.3 9.4 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database